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Showing posts with the label clinical genetics and genomics journal

Do Aging People Have a Higher Risk of Severe COVID Because of Shrinking Chromosomes?

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Overview I shuddered when I remembered Logan's Run, the science fiction classic in which people above a certain age choose to end their lives when I saw a headline in the Washington Post calling COVID "A Plague of the Elderly." In 1976, the year I graduated from college, the movie was released. I would be considered elderly as a result. Indeed, WaPo notes that "almost 9 out of 10 deaths now are in those 65 or older," making elderly people disproportionately affected or killed by COVID. That is remarkable considering that only 16% of people in that age bracket. Even so, few media pieces explore the biology underlying the heightened risk; it's possible that our shorter chromosomes impair the immune response. Journal of Clinical Genetics and Genomics  An open-access journal called Journal of Clinical Genetics and Genomics publishes articles with the goal of figuring out how particular gene mutations affect phenotypes and how to use that knowledge to create nov...

Journal of Clinical Genetics and Genomics

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Understanding the fundamental causes of inherited illnesses and genetic disorders, including Fragile X syndrome, thalassemia, Huntington's disease, cystic fibrosis, down syndrome, mitochondrial disease, muscular dystrophy, and Patau syndrome, is a priority for the Journal of Environmental Microbiology. Studies that use molecular methods to examine illness causation are given particular attention. The article encourages related research on gene therapy to find viable treatments for the disease. Studies using genomic methods, including RNA-Sequencing, ChIP-Sequencing, microarrays, and genetic mapping utilizing next-generation sequencing technology, are strongly advised. Studies looking for mutations or discovering polymorphisms using diagnostic techniques like RAPD and RFLP are also recommended. Articles on the subjects of neurogenetics, cancer genetics, medical genetics, biochemical genetics, population genetics, genetic epidemiology, and immunogenetics are also covered by the Journ...