Do Aging People Have a Higher Risk of Severe COVID Because of Shrinking Chromosomes?
Overview I shuddered when I remembered Logan's Run, the science fiction classic in which people above a certain age choose to end their lives when I saw a headline in the Washington Post calling COVID "A Plague of the Elderly." In 1976, the year I graduated from college, the movie was released. I would be considered elderly as a result. Indeed, WaPo notes that "almost 9 out of 10 deaths now are in those 65 or older," making elderly people disproportionately affected or killed by COVID. That is remarkable considering that only 16% of people in that age bracket. Even so, few media pieces explore the biology underlying the heightened risk; it's possible that our shorter chromosomes impair the immune response. Journal of Clinical Genetics and Genomics An open-access journal called Journal of Clinical Genetics and Genomics publishes articles with the goal of figuring out how particular gene mutations affect phenotypes and how to use that knowledge to create nov...