Research Article: Rhino-Orbito-Cerebral Mucormycosis and its Imaging Spectrum a Prospective Observational and Analytical Study in the Setting of Covid-19 Pandemic in a Tertiary Care Centre, AP, India.

A new research article, curated by Dr. Bomidi Sudha Rani, P. Bujjibabu, M. Umamaheswar Rao and Praveen and titled “Rhino-Orbito-Cerebral Mucormycosis and its Imaging Spectrum a Prospective Observational and Analytical Study in the Setting of Covid-19 Pandemic in a Tertiary Care Centre, AP, India.”, has been published.

Rhino-Orbital-Cerebral Mucormycosis (ROCM) is a potentially fatal fungal infection that commonly affects diabetic and other immunocompromised patients. Necrotizing and Angioinvasive features of this class of pathogenic fungi facilitate the spread from sinuses into orbit and the brain with devastating consequences. Early diagnosis and timely intervention are key to successful treatment.

Aims and Objectives

This article aims to interpret the findings on CT and MRI in ROCM. The primary objective of this study is to enumerate the imaging findings of all patients presented with Rhino orbital cerebral mucormycosis at various stages and to describe the management algorithm. The secondary objective is to follow up on aggressive cases after successful therapy.

The Researchers present 100 cases of ROCM to emphasize the effectiveness of Magnetic Resonance Imaging (MRI) in the diagnosis of this potentially fatal form of mucormycosis. A Favorable outcome was achieved with surgical debridement and prolonged Amphotericin therapy. CT and MR imaging of 100 patients showed predominantly pan-sinus involvement (67%). Extension to the orbit and face (66%) preceded involvement of the deep skull base (62%) and brain (40%). Ontrast-Enhanced Computed Tomography (CECT) showed minimally enhancing hypodense soft tissue thickening as the predominant finding in involved areas, while MRI showed T2 hypointense with post-obstructive T2 hyperintense changes/ soft tissue thickening and heterogeneous post-contrast enhancement as the main finding. Bone erosion was seen less often (40%), with the rest of the patients (60%) showing extra sinus extension across grossly intact appearing bones on imaging.

For further study: Read the article


Comments

Post a Comment

Popular posts from this blog

In a Mexican Hospital, Acetabular Fractures are the Cause of Injury by: Dr. Fernandez

Image
Introduction The study's goal is to determine the relationship between surgically treated acetabular fractures, associated lesions, and the need for pelvic stabilisation before definitive fixation. Retrospective review of patients with acetabular fractures treated surgically at the Mexican Red Cross Central Hospital between August 2013 and January 2016. Descriptive statistical analysis in terms of frequency, proportions, and X2 were performed to determine qualitative dependency among variables, with a P value of 0.05 used to determine significance.32 patients were sampled, 26 of whom were males with an average age of 36.3 years. 75% were caused by an accident involving a motor vehicle (P=0.0052). Damage control orthopaedics were performed in 68.7% of cases, with a positive relationship between this and subsequent surgical treatment (P=0.0052). Damage control orthopaedics were performed in 68.7% of cases, with a positive relationship between this and subsequent surgical treatment (P
Read more

Early Childhood Development: Influences and Interventions in Child Psychology

Image
Introduction Early formative years are a crucial duration of speedy boom and development, laying the foundation for a child's destiny nicely-being. In this weblog post, we are able to explore the importance and significance of early life development, understand the numerous influences on a baby's development, and the interventions and strategies which can promote superb effects. Researchers and pupils from pinnacle universities globally, specifically those interested in infant psychology and early adolescence development, are the audience for this blog publication. The data offered here is based totally on the state-of-the-art study's findings from the Child Psychology Journal . Understanding Early Childhood Development Early formative years of improvement encompass bodily, cognitive, emotional, and social development during the primary few years of life. Key points to keep in mind include: Importance of early formative years: The early years are vital for shaping a child&
Read more

Understanding AIDS and Sexually Transmitted Infections (STIs): What You Need to Know

Image
Sexually transmitted infections (STIs) and acquired immunodeficiency syndrome (AIDS) are serious health concerns that affect millions of people worldwide. They are often misunderstood, and misinformation can contribute to the spread of these infections. In this blog, we will explore the basics of AIDS and STIs, including their causes, transmission, symptoms, prevention, and the importance of getting tested and seeking proper medical care. What is AIDS? AIDS stands for acquired immunodeficiency syndrome, and it is caused by the human immunodeficiency virus (HIV). HIV attacks the immune system, which is responsible for fighting off infections and diseases. Over time, HIV weakens the immune system, making individuals more susceptible to infections and cancers that the body would normally be able to fight off. AIDS is the final stage of HIV infection, characterized by severe immune system damage and the presence of certain opportunistic infections or cancers. What are STIs? Sexually transm
Read more